
Sucralose And Kidney Health: Is Sucralose Bad For Your Kidneys
Many sweeteners such as sucralose and aspartame are now thought to be potentially harmful or bad for organs such as your kidneys. The healthy regulation of our internal organs is crucial for optimal wellbeing. Damage from compounds like sucralose could cause wider health problems within the body.
In the early days artificial sweeteners were thought to be safe. This is because of metabolic inactivity. The food industry considered sweeteners to be a means of reducing obesity and were originally a calorie-free sugar alternative. Sucralose is considered to be 600 times sweeter than sucrose sugar.
Recently the reputation of artificial sweeteners has come under high pressure. The sweetener aspartame is often used in preprepared foods and was just recently designated as a cancer causing compound. Despite this aspartame remains the one of the most extensively used sweeteners in food products annually.
The detection of artificial sweeteners within groundwater supplies in some nations has also raised further concerns about potential toxicological impacts. These findings have led to a well needed reconsideration of the effects of sweeteners such as sucralose.
Studies so far havenโt identified clear evidence that sucralose is a cancer causing compound as with aspartame. There is also similar controversy as to how artificial sweeteners like sucralose could have negative influences on fertility. Some studies have found that sucralose can cause accumulative damage within the body though. This was the subject of a recent study that found some damaging effects from sucralose on kidney tissues.
In this article the potential of sucralose to cause harm to our kidneys and their overall wellbeing will be considered.

Sucralose And Our Health
Sucralose is well known to cause harm to our health and wellbeing. Stand out studies have shown that sucralose intake reduces our sensitivity to sugar and could influence diabetic outcomes.
Other harmful effects from regular sucralose intake include gut microbe changes that promote more pathogenic gut bacteria. Gut microbes influence our wellbeing through brain health and inflammation. This means that sucralose could really harm various aspects our health via these gut microbe changes.
Sucralose intake is linked with inflammation of the gut too. This could affect nutrient intake and susceptibility to specific cancers. Regular sucralose intake could also cause liver inflammation and this is also bad for our overall health.
These are considered to be the most well established effects of sucralose on our overall wellbeing. Other more recent studies have focused on the effects of sucralose within key vital organs such as the kidneys.

How Is Sucralose Bad For The Kidneys
Until recently the effects of the dietary exposure of sucralose on kidney function were unclear. Sucralose has a high metabolic stability and may accumulate in organs within the whole body system. This includes fat tissues where sucralose has been shown to activate inflammatory signals. Some of these include inflammatory cytokines. Only 20% of total ingested sucralose is excreted via the kidneys.
This ability to bioaccumulate makes sucralose a compound of interest regarding potential toxicity within the body. Regular toxin removal is important for our health. This is an important reason as to why sucralose is thought to be bad for our kidneys and kidney health.
There are not many studies that have investigated the harmful effects of sucralose within kidney cells. One recent study has managed to identify some key health issues from sucralose that would influence kidney health and longevity.
This study found that sucralose could worsen injuries to the kidney from toxins that we encounter often in our diet or day to day life. Sucralose may bind to one important detoxifying protein in kidney cells. This protein is critical in removing harmful toxins or drugs from cells and the body. This includes potential cancer causing compounds. In doing so this detoxifying protein helps to keep a healthy balance of compounds within cells that is essential for optimal wellness and survival.
The binding of sucralose to this detoxifying protein would prevent toxin removal and could therefore cause harm to the health of our kidneys. This is a big influencing factor in how sucralose could be bad for the kidneys. A supportive study also revealed that sucralose could interfere with various detoxifying systems within cells and not just this particular detoxifying protein.

Sucralose And Kidney Oxidative Stress
A causative accumulation of one harmful dietary toxin in kidney cells from sucralose intake was discovered in this study. After 90 days of sucralose intake there was a causative worsening of toxin caused kidney dysfunction.
There was also an increase in overall levels of harmful radicals or reactive oxidative species. This increase was also observed in the energy producing mitochondria and this can cause kidney dysfunction. Toxin accumulation causes oxidative stress and can damage vital organs such as the kidneys.
Sucralose accumulation also causes additional oxidative stress and inhibits cell growth too. This is why detoxification and balances in oxidative stress are crucial for cell survival. Healthy detoxification and regulation of oxidative stress is very relevant for kidney health considering how many toxins the kidney encounters each day.
Observed dysfunctions of the kidneys from sucralose and toxin accumulation were reversed with the strong antioxidant NAC. This radical scavenger is also known as N-acetyl cysteine and it may protect the kidneys from toxin caused oxidative stress.
Reducing oxidative stress is very important for optimal kidney health. Accumulated oxidative stress from toxins is a crucial reason as to why sucralose could be bad for our kidneys.
Overall the results from this unique study show that sucralose could be bad for the kidneys and is potentially harmful for our overall health.

Summary
Originally artificial sweeteners were not considered to be harmful for the body. However recent research has identified that compounds like aspartame and sucralose could be potentially harmful for the body. Aspartame is now a cancer causing compound while sucralose is thought to directly influence risk of diabetes.
This has raised a lot of concern around sweeteners. Especially considering how they are used throughout food production and can accumulate in ground water. Sucralose has also been observed to accumulate in the body which makes it of interest for kidney health.
Damage from the accumulation of compounds like sucralose could cause wider health problems within the body. The healthy regulation and maintenance of our internal organs is crucial for optimal wellbeing. One recent study identified that sucralose could be bad for the kidneys.
Sucralose was shown to be able to increase the accumulation of toxins in the kidneys. The regular removal of toxins is important for our health. This a crucial reason as to why sucralose is thought to be bad for our kidneys.
Toxin accumulation adds oxidative stress to the kidneys and could cause kidney dysfunction. This was observed in this study concerning sucralose and the health of the kidneys. The accumulation of sucralose in the body could worsen injuries to the kidney from toxins or drugs we encounter each day.
Sucralose could cause damage to our kidneys via toxin accumulation and resulting increases in oxidative stress. This would impair kidney function. This shows that sucralose could be bad for our kidneys and is potentially harmful for our overall wellbeing.
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